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THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Catalytic receptors.

Stephen Ph Alexander1, Doriano Fabbro2, Eamonn Kelly3

  • 1School of Life Sciences, University of Nottingham Medical School, Nottingham, NG7 2UH, UK.

British Journal of Pharmacology
|September 16, 2021
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Summary

The Concise Guide to Pharmacology 2021/22 offers a comprehensive overview of 1900 human drug targets, emphasizing selective pharmacology. This biennial publication provides a citable record of drug target information, complementing the online knowledgebase.

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Area of Science:

  • Pharmacology
  • Drug Discovery
  • Biomedical Science

Background:

  • The Concise Guide to Pharmacology is a biennial publication series.
  • It serves as a crucial resource for understanding human drug targets and their properties.

Purpose of the Study:

  • To present a concise overview of nearly 1900 human drug targets.
  • To emphasize selective pharmacology and provide links to a detailed online knowledgebase.
  • To offer a permanent, citable record of drug target information.

Main Methods:

  • Compilation of data on human drug targets, focusing on key properties.
  • Tabular format presentation for concise overviews.
  • Inclusion of links to the www.guidetopharmacology.org knowledgebase for detailed information.

Main Results:

  • Provides information on approximately 1900 human drug targets.
  • Organizes targets into six major categories: catalytic receptors, G protein-coupled receptors, ion channels, nuclear hormone receptors, enzymes, and transporters.
  • Includes nomenclature guidance, information on pharmacological tools, references, and further reading suggestions.

Conclusions:

  • The Concise Guide to Pharmacology 2021/22 is an essential, up-to-date reference for researchers.
  • It offers a valuable snapshot of drug target information, complementing online resources.
  • The publication, in conjunction with NC-IUPHAR, provides official IUPHAR classification and nomenclature.