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COVID-19 in older adults
Saket Saxena1, Ardeshir Z Hashmi2
1Department of Internal Medicine and Geriatrics, Cleveland Clinic, Cleveland, OH SAXENAS@ccf.org.
Older adults over 65 are disproportionately affected by COVID-19, experiencing more severe illness and higher mortality. This review covers their unique clinical presentations, challenges, and treatment strategies.
Area of Science:
- Gerontology
- Infectious Diseases
- Public Health
Background:
- COVID-19 severity and mortality significantly increase in individuals aged 65 and older.
- Aging-related pathophysiologic changes and immune dysregulation contribute to atypical disease presentations in older adults.
- Chronic comorbidities exacerbate the impact of COVID-19 in the elderly population.
Purpose of the Study:
- To review the clinical presentations of COVID-19 in older adults.
- To identify the unique challenges faced by this demographic during the pandemic.
- To discuss effective treatment strategies for COVID-19 in the elderly.
Main Methods:
- Literature review of clinical presentations.
- Analysis of age-specific COVID-19 impact data.
- Synthesis of current treatment guidelines for older adults.
Main Results:
- Older adults exhibit atypical COVID-19 symptoms, differing from younger populations.
- Increased risk of severe outcomes, including hospitalization and death, is evident in those over 65.
- Management requires tailored approaches considering comorbidities and physiological changes.
Conclusions:
- COVID-19 poses a significant threat to older adults, necessitating specialized care.
- Understanding atypical presentations is crucial for timely diagnosis and intervention.
- Effective management strategies are vital to mitigate morbidity and mortality in this vulnerable group.
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