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A Femtoliter Droplet Array for Massively Parallel Protein Synthesis from Single DNA Molecules
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Droplets take DNA by force

Marina Feric1,2

  • 1National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.

Nature Physics
|September 17, 2021
PubMed

Abstract:

Single-molecule experiments can now quantify the surface forces that compete to package tethered DNA into a protein-rich condensate - providing much-needed mechanistic insight into the phase behaviour of the entangled genome in the nucleus.

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