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Shock in China 2018 (SIC-study): a cross-sectional survey
Longxiang Su1, Xudong Ma2, Xi Rui1
1Department of Critical Care Medicine, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Peking Union Medical College & Chinese Academy of Medical Sciences, Beijing, China.
Insights
Shock is a critical illness with high mortality. This study identified cardiogenic shock as having the highest in-hospital mortality, with malignant tumors being a key factor in patient deaths.
Area of Science:
- Critical care medicine
- Epidemiology
- Health services research
Background:
- Shock represents a life-threatening critical illness with significant patient mortality.
- Understanding the epidemiology and mortality of shock is crucial for improving patient outcomes.
- Identifying factors associated with hospital death in shock patients is essential for targeted interventions.
Purpose of the Study:
- To elucidate the epidemiology of shock in China.
- To determine the mortality rates associated with different types of shock.
- To identify key factors contributing to in-hospital mortality among shock patients.
Main Methods:
- A multi-center, cross-sectional survey was conducted across 1,064 tertiary hospitals in China.
- Data from 289,428 patients diagnosed with shock (ICD-10) were extracted from the Hospital Quality Monitoring System (HQMS) in 2018.
- Regression analysis was employed to identify factors associated with hospital death.
Main Results:
- Hypovolemic shock (44.38%) and septic shock (41.99%) were the most prevalent types.
- Cardiogenic shock exhibited the highest in-hospital mortality rate (31.6%), followed by obstructive (25.2%), septic (22.9%), and hypovolemic shock (15.5%).
- The presence of malignant tumors was identified as a significant factor related to hospital deaths in shock patients.
Conclusions:
- Shock is a severe condition characterized by high fatality rates and substantial clinical costs.
- This 2018 epidemiological survey in China highlights the need to clarify factors influencing hospital death in shock cases.
- Targeted strategies addressing specific shock types and comorbidities like malignant tumors are necessary to reduce mortality.
Background:
Shock is a critical illness that seriously threatens the lives of patients. This study explains the epidemiology of shock, mortality of shock, and identify factors that related to hospital death.
Methods:
This is a multi-centre cross-sectional survey, which included 1,064 tertiary hospitals in 31 provinces, municipalities, and autonomous regions across China mainland. Totally 289,428 patients who diagnosed with shock based on the ICD-10 abstracted from the Hospital Quality Monitoring System (HQMS) in 2018, a national database administrated by National Health Commission of the PRC.
Results:
Patients diagnosed with shock were screened and classified according to the type of shock. Regression analysis was used to identify factors that related to death. A total of 79,668,156 medical records were included in HQMS in 2018, from which a total of 289,428 records with shock were identified. Hypovolemic shock occurred in 128,436 cases (44.38%), septic shock occurred in 121,543 cases (41.99%), cardiogenic shock occurred in 44,597 cases (15.41), and obstructive shock occurred in 3,168 cases (1.09%). Of these, 8,147 cases (2.81%) had mixed shock, which means had two or more types of shock. For all the shock cases, the top three frequent concomitant diseases recorded were circulatory system diseases (55.22%), digestive system diseases (53.64%), and respiratory system diseases (53.31%). Of the four types of shock, cases with cardiogenic shock had the highest in-hospital mortality (31.6%), followed by those with obstructive shock (25.2%), septic shock (22.9%), and hypovolemic shock (15.5%). Interestingly, the combination of shock and malignant tumors is one of the major factors that related to hospital deaths.
Conclusions:
Shock is a serious disease with a high fatality rate and huge clinical costs. According to this epidemiological survey of shock in China 2018, we should clarify the factors related to the hospital death in shock cases.
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