Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Head and Neck Free Flap Reconstruction: Current Landscape and Emerging Technologies.

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery·2026
Same author

Posterior Nasal Neurectomy for Allergic and Non-Allergic Rhinitis: Efficacy, Safety, and Predictive Factors.

ORL; journal for oto-rhino-laryngology and its related specialties·2026
Same author

Digital Pathology in Head and Neck Squamous Cell Carcinoma: Translational Advances and Clinical Integration for Pathologists, Oncologists, and Surgeons.

Head and neck pathology·2026
Same author

Impact of Generative AI on Operative Planning in Otolaryngology Residents.

Surgical innovation·2026
Same author

From Lobectomy to Completion Thyroidectomy: A Cohort Study and Systematic Review.

Clinical endocrinology·2026
Same author

Translation and Validation of the MD Anderson Dysphagia Inventory (MDADI) for Hebrew-Speaking Patients.

Head & neck·2026

Related Experiment Video

Updated: Oct 19, 2025

Intraoperative Assessment of Resection Margins in Oral Cavity Cancer: This is the Way
04:45

Intraoperative Assessment of Resection Margins in Oral Cavity Cancer: This is the Way

Published on: May 10, 2021

4.0K

Is intraoperative margin sampling necessary in inverted papilloma resection?

Eran Glikson1,2, Alberto Dragonetti3, Ethan Soudry4,5

  • 1Department of Otolaryngology Head and Neck Surgery, The Sheba Medical Center, Tel Hashomer, Israel. Eran.Glikson@sheba.health.gov.il.

European Archives of Oto-Rhino-Laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
|September 17, 2021
PubMed
Summary

Routine intraoperative margin sampling during inverted papilloma (IP) surgery does not impact recurrence rates. However, extending surgery based on positive frozen sections was linked to higher recurrence, questioning the routine use of this technique.

Keywords:
Endoscopic endonasal resectionFrozen sectionInverted papillomaSurgical margins

More Related Videos

Author Spotlight: 3D Scanning and Augmented Reality for Enhanced Cancer Surgery Communication
07:47

Author Spotlight: 3D Scanning and Augmented Reality for Enhanced Cancer Surgery Communication

Published on: December 15, 2023

905
Intraoperative Gastroscopy for Tumor Localization in Laparoscopic Surgery for Gastric Adenocarcinoma
10:31

Intraoperative Gastroscopy for Tumor Localization in Laparoscopic Surgery for Gastric Adenocarcinoma

Published on: August 9, 2016

12.9K

Related Experiment Videos

Last Updated: Oct 19, 2025

Intraoperative Assessment of Resection Margins in Oral Cavity Cancer: This is the Way
04:45

Intraoperative Assessment of Resection Margins in Oral Cavity Cancer: This is the Way

Published on: May 10, 2021

4.0K
Author Spotlight: 3D Scanning and Augmented Reality for Enhanced Cancer Surgery Communication
07:47

Author Spotlight: 3D Scanning and Augmented Reality for Enhanced Cancer Surgery Communication

Published on: December 15, 2023

905
Intraoperative Gastroscopy for Tumor Localization in Laparoscopic Surgery for Gastric Adenocarcinoma
10:31

Intraoperative Gastroscopy for Tumor Localization in Laparoscopic Surgery for Gastric Adenocarcinoma

Published on: August 9, 2016

12.9K

Area of Science:

  • Otolaryngology
  • Surgical Pathology

Background:

  • Inverted papilloma (IP) is a benign neoplasm of the sinonasal tract with a significant recurrence rate.
  • Intraoperative margin assessment aims to ensure complete tumor resection and minimize recurrence.

Purpose of the Study:

  • To investigate the association between intraoperative frozen section margin sampling and recurrence rates following inverted papilloma resection.

Main Methods:

  • A multicenter retrospective study analyzed 220 patients undergoing attachment-oriented IP resection.
  • Follow-up was a minimum of 36 months, with a mean of 49 months.

Main Results:

  • Overall recurrence rate was 10.45%.
  • No significant difference in recurrence was observed between groups with and without intraoperative margin sampling (p=0.44).
  • However, cases with extended surgery due to positive frozen sections showed a significantly higher recurrence rate (OR=6.94).

Conclusions:

  • Intraoperative margin sampling via frozen section does not appear to influence the recurrence of inverted papilloma.
  • The routine utilization of intraoperative margin sampling in IP surgery warrants re-evaluation.