[Review of clinical practice guidelines for hypoparathyroidism]

Area of Science:

• Endocrinology
• Metabolic Disorders
• Surgical Complications

Background:

• Hypoparathyroidism is characterized by low parathyroid hormone, impairing calcium-phosphorus balance.
• Neck surgery is the primary cause, with increasing incidence expected due to thyroid and other neck pathologies.
• Autoimmune hypoparathyroidism, often in childhood, presents severely, especially with malabsorption.

Purpose of the Study:

• To review the 2021 Russian guidelines for chronic hypoparathyroidism management.
• To outline diagnostic, therapeutic, and follow-up strategies.
• To address special patient groups, including those with acute hypocalcemia and pregnancy.

Main Methods:

• Review of the 2021 Russian guidelines for chronic hypoparathyroidism.
• Analysis of laboratory and instrumental evaluation methods.
• Examination of treatment approaches and follow-up protocols.

Main Results:

• Guidelines emphasize lifelong, multicomponent therapy with individualized treatment strategies.
• Inadequate management increases risks of renal, cardiovascular, musculoskeletal, and neurocognitive complications.
• Timely diagnosis and rational therapy can reduce complications, hospitalizations, and disability.

Conclusions:

• Adherence to the 2021 Russian guidelines is crucial for effective chronic hypoparathyroidism management.
• Comprehensive evaluation, tailored therapy, and diligent follow-up are essential.
• Guidelines provide critical recommendations for diverse patient populations, improving outcomes.