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Chronic Recurrent Multifocal Osteomyelitis Involving the Mandible - A Rare Case Report.

Abrar Alamoudi, Niranzena Panneer Selvam, Deeba Kashtwari

    The Journal of Clinical Pediatric Dentistry
    |September 17, 2021
    PubMed
    Summary

    Chronic recurrent multifocal osteomyelitis (CRMO) is a rare bone condition causing painful lesions. This case highlights CRMO in the mandible, emphasizing diagnostic challenges and the need for radiologist awareness.

    Keywords:
    Chronic multifocal osteomyelitisMultifocal osteomyelitischronic osteomyelitis

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    Area of Science:

    • Pediatric Rheumatology
    • Osteology
    • Radiology

    Background:

    • Chronic recurrent multifocal osteomyelitis (CRMO) is an aseptic autoinflammatory bone disorder.
    • CRMO typically presents with multifocal bone lesions, pain, swelling, and recurrent episodes.
    • Mandibular involvement in CRMO is rare, unlike common sites like the clavicle and long bone metaphyses.

    Observation:

    • This case report details a rare instance of CRMO affecting the mandible.
    • The study focuses on the clinical and radiographic features of mandibular CRMO.
    • Diagnosis is often achieved by excluding other conditions, including infectious osteomyelitis.

    Findings:

    • CRMO lesions lack identifiable etiology or microbiological findings.
    • Misdiagnosis can lead to unnecessary antibiotic treatments, radiation exposure, and bone biopsies.
    • Radiographic recognition is crucial for timely diagnosis of mandibular CRMO.

    Implications:

    • Increased radiologist familiarity with CRMO can facilitate earlier diagnosis.
    • Prompt diagnosis aids in formulating appropriate, non-antibiotic-based treatment plans.
    • This case underscores the importance of considering CRMO in mandibular bone lesions.