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Updated: Oct 19, 2025

Predicting the Effectiveness of Population Replacement Strategy Using Mathematical Modeling
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Challenges on the interaction of models and policy for pandemic control
Liza Hadley1, Peter Challenor2, Chris Dent3
1Disease Dynamics Unit, Department of Veterinary Medicine, University of Cambridge, United Kingdom.
Abstract:
The COVID-19 pandemic has seen infectious disease modelling at the forefront of government decision-making. Models have been widely used throughout the pandemic to estimate pathogen spread and explore the potential impact of different intervention strategies. Infectious disease modellers and policymakers have worked effectively together, but there are many avenues for progress on this interface. In this paper, we identify and discuss seven broad challenges on the interaction of models and policy for pandemic control. We then conclude with suggestions and recommendations for the future.
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