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Published on: September 15, 2020
Problems associated with the use of the term "antibiotics"
Roland Seifert1, Bastian Schirmer2
1Institute of Pharmacology, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany. seifert.roland@mh-hannover.de.
The term "antibiotics" is a misnomer for antibacterial drugs. This study advocates for precise terminology, like "antibacterial drugs," to improve clarity and accommodate drug repurposing for new indications.
Area of Science:
- Pharmacology
- Microbiology
- Drug Nomenclature
Background:
- The term "antibiotics" is widely misused for antibacterial drugs.
- Existing terminology like "antibiosis" and "antibiogram" is also imprecise.
- Drug repurposing necessitates clearer drug class designations.
Purpose of the Study:
- To advocate for replacing "antibiotics" with "antibacterial drugs."
- To argue against the use of imprecise terms like "narrow-spectrum" and "reserve antibiotics."
- To promote explicit use of "drug" to encompass new indications.
Main Methods:
- Literature review of term usage.
- Analysis of traditional versus precise terminology.
- Examination of drug repurposing examples.
Main Results:
- Traditional terms like "antibiotics" are more prevalent than precise alternatives.
- Terms such as "narrow-spectrum antibiotics," "reserve antibiotics," "chemotherapeutics," and "tuberculostatics" should be discontinued.
- Antibacterial drugs are used for non-antibacterial purposes, and vice versa, highlighting nomenclature issues.
Conclusions:
- Adopting precise drug class nomenclature is crucial for scientific accuracy.
- Explicitly using "drug" facilitates understanding of expanded therapeutic roles.
- A rational nomenclature system is essential for pharmacology.
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