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Updated: Oct 19, 2025

Planarian as an Animal Model for Experimental Acute Seizure
Published on: February 14, 2025
Differential accumulation of PAHs within planarian cephalic and posterior body parts
Fátima C P Simão1, Ana L Machado2, Amadeu M V M Soares1
1CESAM - Centre for Environmental and Marine Studies & Department of Biology, University of Aveiro, Aveiro, Portugal.
Abstract:
It has been observed that freshwater planarians can accumulate cadmium in their head portions, with neurotoxicity and head loss accompanying this phenomenon. Since planarians exhibit head loss and symptoms of neurotoxicity in response to PAHs, we investigated the differential accumulation of pyrene and B[a]P in the body and head portions of Girardia tigrina, a freshwater planarian. It is evidenced that planarian head fragments present higher amounts of pyrene- and B[a]P-equivalents than body fragments, indicating a differential distribution of these compounds within planarian tissues.
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