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Updated: Oct 19, 2025

Direct Mouse Trauma/Burn Model of Heterotopic Ossification
Published on: August 6, 2015
Neurogenic heterotopic ossification in the upper limb
N Sturbois-Nachef1, L Gatin2, M Salga3
1Clinique d'orthopédie-traumatologie, Hôpital R. Salengro, CHU de Lille, Rue E. Laine, 59037 Lille Cedex, France.
Abstract:
Neurogenic heterotopic ossifications (NHOs) are periarticular ectopic ossifications that frequently develop after a central nervous system injury, most often a traumatic one. They limit range of motion and cause pain, interfering with limb positioning and function, whether active or passive. Highly described in the lower limbs, NHOs can also develop in the upper limb, with specific characteristics depending on their location. This article provides a summary of the diagnostic and therapeutic management of NHOs in the upper limb, based on the current literature.
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