Rose petals-like Bi semimetal embedded on the zeolitic imidazolate frameworks based-immunochromatographic strip to...

Ultrasensitive and facile detection of Acetamiprid (ACE) is of exceptional significance to assess the environmental and biological pollution. In this study, an advanced Bi semimetal/Zeolitic imidazolate frameworks hybrid material-based immunochromatographic strip (Bi/ZIF HM-ICS) sensor was developed for the sensitive detection of ACE. The novel Bi/ZIF HM was prepared through one-pot hydrothermal reduction of Bi nanoparticles on ZIF, which was selected as a signal tag taking advantages of its excellent color intensity, strong affinity with monoclonal antibodies (mAbs), and favorable biocompatibility. Bi/ZIF HM could not only improve the utilization efficiency of mAbs but also boost the sensing performance. Under optimal conditions, the limit of detection (LOD) of the Bi/ZIF HM-ICS was 4.68 pg/mL with the linear range from 0.01 ng/mL to 6 ng/mL, which was 98-fold lower than that of traditional gold nanoparticles-based ICS (0.457 ng/mL), and the recoveries of the Bi/ZIF HM-ICS ranged from 80.27% to 118.52% with the relative standard deviation (RSD) below 3.67% in pear, apple, tomato, and cucumber. Overall, the practical application of the Bi/ZIF HM-ICS in complicated samples was realized for detecting pesticide residue, and expanding its application scope in monitoring environment.