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Related Experiment Videos

[Renal complications due to desensitization].

M Drouet1, A Sabbah, J C Bonneau

  • 1Laboratorie d'Immuno-Allergologie, C.H.U. Angers, France.

Allergie Et Immunologie
|April 1, 1986
PubMed
Summary

Immunotherapy can cause kidney complications like proteinuria and hematuria. These adverse events occurred rapidly after venom and insect extract treatments, highlighting potential risks.

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Area of Science:

  • Immunology
  • Nephrology

Background:

  • Immunotherapy is a treatment that uses the immune system to fight disease.
  • Adverse reactions to immunotherapy can occur, necessitating careful monitoring.

Observation:

  • Two cases of renal complications during immunotherapy are presented.
  • The first patient experienced proteinuria and infection after rush immunotherapy with Yellow Jacket Venom Extract.
  • The second patient developed rhinitis, conjunctivitis, and hematuria after "half-rush" immunotherapy with phleole extract.

Findings:

  • Rapid onset of proteinuria and infection following rush immunotherapy.
  • Immediate allergic reactions and delayed macroscopic hematuria after sub-rush immunotherapy.

Implications:

  • These cases underscore the importance of vigilant monitoring for renal complications during immunotherapy.
  • Further research into predicting and mitigating these adverse events is warranted.

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