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Related Concept Videos

Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

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Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
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Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

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Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
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Myocarditis II: Clinical Features and Diagnostic Tests01:27

Myocarditis II: Clinical Features and Diagnostic Tests

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Myocarditis is an inflammation of the heart muscle. The symptoms vary widely, encompassing asymptomatic presentations to severe, acute manifestations.Clinical PresentationAsymptomatic cases: In some instances, myocarditis may be asymptomatic, with the infection resolving without intervention. These cases often go undetected unless discovered incidentally through diagnostic imaging or tests conducted for other reasons.General Early Symptoms: Early symptoms of myocarditis are non-specific and can...
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Nephrotic Syndrome I : Introduction01:24

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Nephrotic Syndrome is a chronic kidney disorder defined by clinical findings such as severe proteinuria, hypoalbuminemia, hyperlipidemia, and edema. These symptoms result from damage to the glomeruli, the kidney’s filtering units, increasing their permeability to proteins.Definition and Meaning:Proteinuria, defined as the loss of more than 3.5 grams of protein per day in adults, is a crucial feature of nephrotic syndrome. This condition is often accompanied by edema, the accumulation of...
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Related Experiment Video

Updated: Oct 19, 2025

Separation of Immune Cell Subpopulations in Peripheral Blood Samples from Children with Infectious Mononucleosis
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Multisystem Inflammatory Syndrome in Children.

Muhammad Waseem1, Masood A Shariff2, Ee Tein Tay3

  • 1Department of Emergency Medicine, NYC Health + Hospitals/Lincoln, Bronx, New York; Weill Cornell Medicine New York and New York Medical College, Valhalla, New York.

The Journal of Emergency Medicine
|September 20, 2021
PubMed
Summary
This summary is machine-generated.

Multisystem inflammatory syndrome in children (MIS-C) is a serious condition linked to COVID-19. Early recognition and treatment are vital for better outcomes in affected children.

Keywords:
COVID-19Kawasaki diseasePMISSARS-CoV-2multisystem inflammatory syndrome in children

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Area of Science:

  • Pediatric Infectious Diseases
  • Immunology
  • Critical Care Medicine

Background:

  • Multisystem inflammatory syndrome in children (MIS-C) is a novel condition associated with COVID-19.
  • MIS-C shares clinical features with Kawasaki disease (KD) and toxic shock syndrome (TSS).

Purpose of the Study:

  • To review current literature on MIS-C.
  • To outline evaluation and treatment algorithms for suspected MIS-C in emergency departments.

Main Methods:

  • Literature review of MIS-C cases.
  • Analysis of diagnostic criteria and treatment protocols.

Main Results:

  • MIS-C presents with a broad clinical spectrum involving multiple organ systems.
  • Diagnosis relies on clinical presentation and laboratory findings, with frequent gastrointestinal, cardiac, and coagulopathy issues.
  • High suspicion is crucial for COVID-19 exposed children.

Conclusions:

  • Early diagnosis and prompt treatment of MIS-C are critical for optimal patient outcomes.
  • Management requires a multidisciplinary approach in emergency settings.