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Pubertal development in girls. Variability and interrelationships.

R H Largo1, A Prader

  • 1Universitäts-Kinderspital Zürich, Switzerland.

Pediatrician
|January 1, 1987
PubMed
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Pubertal development shows significant normal variation in secondary sex characteristics, height growth, and menstrual cycles. Understanding this variability is key to identifying potential somatic disturbances during puberty.

Area of Science:

  • Pediatrics
  • Endocrinology
  • Human Growth and Development

Background:

  • Pubertal development exhibits considerable variability, often leading to concerns about somatic disturbances.
  • Accurate data on normal pubertal progression is essential for clinical assessment.

Purpose of the Study:

  • To provide data on the normal variation in key aspects of pubertal development.
  • To discuss the interrelationships between pubertal signs, growth, and bone age.

Main Methods:

  • Utilized data from the First Zurich Longitudinal Study.
  • Analyzed variations in secondary sex characteristics, height growth, and menstrual cycles.

Main Results:

  • Established normative data for normal pubertal development parameters.

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  • Detailed the interplay between the onset of pubertal signs, height velocity, and skeletal maturation.

    • Conclusions:

    • Normal variation in pubertal development is extensive.
    • Clinically relevant data aids in distinguishing normal progression from potential disturbances.