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The relationship between CHA2DS2-VASc score and isolated coronary artery ectasia

Hasan Ali Barman1, Adem Atici2, Gokhan Alici3

  • 1Department of Cardiology, Institute of Cardiology, Istanbul University-Cerrahpaşa Istanbul, Turkey.

American Journal of Blood Research
|September 20, 2021
PubMed

Insights

The CHA2DS2-VASc score, a measure of cardiovascular risk, was significantly higher in patients with coronary artery ectasia (CAE). This score may help predict thrombus formation in individuals with CAE.

Area of Science:

  • Cardiology
  • Vascular Biology

Background:

  • Coronary artery ectasia (CAE) involves abnormal widening of coronary arteries.
  • Understanding risk factors and associated conditions is crucial for managing CAE.

Purpose of the Study:

  • To investigate the association between the CHA2DS2-VASc score and the presence of isolated coronary artery ectasia (CAE).

Main Methods:

  • A case-control study compared 122 patients with isolated CAE to 87 controls.
  • Demographic, clinical, laboratory data, and CHA2DS2-VASc scores were analyzed.
  • Multivariate logistic regression identified independent predictors of CAE.

Main Results:

  • Patients with CAE had significantly higher CHA2DS2-VASc scores (2.41 ± 1.12) compared to controls (1.52 ± 0.73).
  • Independent predictors of CAE included higher CHA2DS2-VASc score, uric acid, white blood cell count, hs-CRP, and smoking.
  • Lower left ventricular ejection fraction was also associated with CAE.

Conclusions:

  • Elevated CHA2DS2-VASc scores are linked to isolated coronary artery ectasia.
  • The CHA2DS2-VASc score may serve as a valuable tool for predicting coronary thrombus development in CAE patients.
Abstract

Keywords:
CHA2DS2-VASc scorecoronary artery diseaseectasia

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