Computational Horizons In Cancer (CHIC): Developing Meta- and Hyper-Multiscale Models and Repositories for In Silico...

Area of Science:

• Computational biology
• Biomedical engineering
• Transatlantic research collaboration

Background:

• The need for integrated, large-scale research projects in biomedical science.
• Advancements in computational modeling and simulation.

Purpose of the Study:

• To outline the aim, objectives, architecture, and building blocks of the CHIC project.
• To provide an overview of a major transatlantic research initiative.

Main Methods:

• Describing the project's architectural design.
• Identifying the core components and building blocks.
• Integrating transatlantic research efforts.

Main Results:

• A conceptual framework for the CHIC project.
• Identification of key technological and scientific components.
• Establishment of a collaborative transatlantic research network.

Conclusions:

• The CHIC project represents a significant step in integrating complex biological system research.
• The project's architecture and building blocks are foundational for future advancements in the virtual physiological human.
• Successful transatlantic collaboration is crucial for large-scale scientific endeavors.