Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Specific immunotherapy in hay fever.

K Obtulowicz, E Sanokowska, J Radwan

    Allergie Et Immunologie
    |March 1, 1987
    PubMed
    Summary

    Specific immunotherapy (SI) for hay fever (HF) showed effectiveness in 47% of patients over three years. While beneficial for many, 17% experienced side effects including HF exacerbation.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Widespread Adaptive Introgression of Major Histocompatibility Complex Genes across Vertebrate Hybrid Zones.

    Molecular biology and evolution·2024
    Same author

    Bradykinin mediated gastrointestinal edema as a cause of abdominal attacks in patients with hereditary angioedema due to C1-inhibitor deficiency.

    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society·2022
    Same author

    Water and ion diffusion in partially-water saturated compacted kaolinite: Role played by vapor-phase diffusion in water mobility.

    Journal of contaminant hydrology·2022
    Same author

    Sexual selection drives the evolution of male wing interference patterns.

    Proceedings. Biological sciences·2019
    Same author

    Diffusion of organic anions in clay-rich media: Retardation and effect of anion exclusion.

    Chemosphere·2018
    Same author

    De novo transcriptome assembly facilitates characterisation of fast-evolving gene families, MHC class I in the bank vole (Myodes glareolus).

    Heredity·2016

    Area of Science:

    • Allergy and Immunology
    • Immunotherapy Research
    • Clinical Trials in Allergy

    Background:

    • Hay fever (HF) affects a significant portion of the population, leading to reduced quality of life.
    • Current treatments for HF vary in efficacy and potential side effects.
    • Specific immunotherapy (SI) is a treatment option aimed at modifying the immune response to allergens.

    Purpose of the Study:

    • To evaluate the efficacy and safety of specific immunotherapy (SI) in patients with hay fever (HF).
    • To assess immunological markers and clinical outcomes following three years of SI treatment.
    • To identify the incidence and nature of side effects associated with SI in HF patients.

    Main Methods:

    • A cohort of 120 patients aged 18-58 with hay fever (HF) was observed.
    • 77 patients received three consecutive years of specific immunotherapy (SI) with a pollen vaccine.
    • 43 patients served as a control group, not receiving SI.

    Main Results:

    • Specific immunotherapy (SI) was effective in 47% of treated hay fever (HF) patients.
    • Effective SI cases showed normalized IgE levels, increased IgG levels, and suppressed skin test reactivity to pollen allergens.
    • 17% of patients undergoing SI experienced side effects, including HF exacerbation and increased skin reactions to pollen allergens.

    Conclusions:

    • Specific immunotherapy (SI) demonstrates significant efficacy in a subset of hay fever (HF) patients.
    • Monitoring for side effects is crucial during SI treatment, as adverse reactions can occur.
    • SI offers a potential long-term treatment strategy for allergic rhinitis by modulating immune responses.

    Related Experiment Videos