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Updated: Oct 19, 2025

Assessment of Child Anthropometry in a Large Epidemiologic Study
Published on: February 2, 2017
Body Mass Index Category and Adverse Events in Hospitalized Children
Elizabeth Eby Halvorson1, Danielle P Thurtle2, Ashley Easter1
1Department of Pediatrics, Wake Forest School of Medicine (EE Halvorson and A Easter), Winston-Salem, NC.
Insights
This study found no link between a child's body mass index (BMI) category and the rate or severity of adverse events (AEs). However, initial findings suggested a higher rate of preventable AEs in children with obesity.
Area of Science:
- Pediatric patient safety
- Clinical outcomes research
- Body Mass Index (BMI) and health
Background:
- Adverse events (AEs) in pediatric populations can impact patient outcomes.
- Understanding the relationship between body mass index (BMI) categories and AEs is crucial for targeted interventions.
- Previous research has not definitively established a link between BMI and AE rates, severity, or preventability in children.
Purpose of the Study:
- To investigate the association between patient body mass index (BMI) category and adverse event (AE) rate, severity, and preventability.
- To analyze AE data in a cohort of children discharged from an academic children's hospital.
- To identify potential risk factors related to BMI in pediatric patient safety.
Main Methods:
- Retrospective cohort study of 680 pediatric patients (ages 2-17) discharged between June and October 2018.
- Patients categorized into underweight, normal weight, overweight, and obesity based on BMI.
- Adverse events identified using the Global Assessment of Pediatrics Patient Safety trigger tool and scored for harm and preventability.
Main Results:
- A total of 270 AEs were recorded across 834 encounters.
- No significant association was found between BMI category and the overall rate of AEs (P = .46).
- No associations were observed between BMI category and AE severity; initial analysis suggested increased preventable AEs in obesity, but this did not persist in multivariable modeling.
Conclusions:
- This single-center study did not establish a clear association between BMI category and the rate, severity, or preventability of AEs in pediatric patients.
- Further research with larger, diverse cohorts may be needed to explore subtle relationships.
- Current findings suggest that BMI category alone may not be a primary predictor of AEs in this pediatric population.
Objective:
To identify associations between patient body mass index (BMI) category and adverse event (AE) rate, severity, and preventability in a cohort of children discharged from an academic children's hospital.
Methods:
We identified patients 2 to 17 years old consecutively discharged between June and October 2018. Patient age, sex, height, and weight were used to categorize patients as having underweight, normal weight, overweight, or obesity. We used the Global Assessment of Pediatrics Patient Safety trigger tool to identify AEs, which were scored for harm and preventability. The primary outcome was the rate of AEs; these were compared with Poisson regression. We used multivariable logistic regression to model event preventability.
Results:
We reviewed 834 encounters in 680 subjects; 51 (7.5%) had underweight, 367 (54.0%) had normal weight, 112 (16.5%) had overweight, and 150 (22.1%) had obesity. Our cohort experienced 270 AEs, with an overall rate of 69.7 (61.8-78.5) AEs per 1000 patient-days: 67.7 (46.4-98.7) in underweight, 70.0 (59.4-82.4) in normal weight, 58.6 (42.5-79.7) in overweight, and 80.4 (62.5-103.6) in obesity, P = .46. No associations were seen between BMI category and AE severity. Children with obesity had an increased rate of preventable AEs (P < .01), but this association did not persist in the multivariable model.
Conclusions:
In this single-center study, we did not find associations between BMI category and rate, severity, or preventability of AEs.
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