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Skin Diseases and Disorders01:23

Skin Diseases and Disorders

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Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
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Skin manifestations associated with systemic diseases - Part I.

Ana Luisa Sampaio1, Aline Lopes Bressan1, Barbara Nader Vasconcelos1

  • 1Hospital Universitário Pedro Ernesto, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.

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Summary

The skin reflects internal health, offering diagnostic clues for systemic diseases beyond its barrier function. This review details cutaneous manifestations of rheumatologic, vascular, and granulomatous conditions, aiding dermatologists in comprehensive patient assessment.

Keywords:
DermatomyositisPyoderma gangrenosumSarcoidosisSweet syndromeSystemic lupus erythematosusSystemic sclerodermaVasculitis

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Area of Science:

  • Dermatology and Systemic Diseases
  • Internal Medicine-Dermatology Interface

Background:

  • The skin serves as a visible indicator of underlying systemic conditions.
  • Dermatologists play a crucial role in identifying systemic diseases through cutaneous manifestations.

Purpose of the Study:

  • To provide a comprehensive overview of dermatological manifestations across various systemic diseases.
  • To serve as a practical consultation material for dermatologists.

Main Methods:

  • Review of cutaneous manifestations associated with major rheumatologic diseases.
  • Discussion of vascular and granulomatous diseases with dermatologic relevance.
  • Exploration of dermatologic signs in endocrinological, hematological, oncological, cardiovascular, renal, and gastrointestinal conditions.

Main Results:

  • Specific and non-specific skin alterations can aid in diagnosing systemic diseases.
  • Cutaneous manifestations of rheumatologic diseases are highlighted as a key area of dermatological interface.
  • The article covers a broad spectrum of systemic diseases and their skin presentations.

Conclusions:

  • Comprehensive dermatological assessment is vital for diagnosing systemic illnesses.
  • Understanding skin signs aids in early detection and management of internal diseases.
  • This review aims to enhance dermatologists' diagnostic capabilities through accessible information.