Related Experiment Video
Updated: Oct 19, 2025

Acupoint Catgut Embedding Therapy in Traditional Chinese Medicine for Managing Allergic Rhinitis
Published on: December 20, 2024
Pediatric allergic fungal rhinosinusitis: optimizing outcomes
Masanobu Suzuki1,2, James Connell1, Alkis James Psaltis1
1Department of Surgery-Otorhinolaryngology Head and Neck Surgery, Central Adelaide Local Health Network and the Department of Surgery, Faculty of Health Sciences, University of Adelaide, Adelaide, South Australia, Australia.
Allergic fungal rhinosinusitis (AFRS) in children requires early diagnosis and treatment. Endoscopic sinus surgery followed by corticosteroids is the standard care for this aggressive condition.
Area of Science:
- Pediatric Otolaryngology
- Allergy and Immunology
- Rhinosinusitis Research
Background:
- Allergic fungal rhinosinusitis (AFRS) is a severe condition in children, with limited pediatric-specific reviews available.
- Pediatric AFRS shares characteristics with adult forms but presents more aggressively, including higher IgE levels and facial bone abnormalities.
Purpose of the Study:
- To review recent evidence on pediatric AFRS.
- To provide insights for optimizing treatment outcomes in children with AFRS.
Main Methods:
- Review of current pediatric literature on Allergic Fungal Rhinosinusitis.
- Analysis of clinical characteristics, diagnostic criteria, and treatment modalities.
Main Results:
- Pediatric AFRS involves nasal polyposis, fungal hypersensitivity, eosinophilic mucin, and peripheral eosinophilia.
- Diagnosis utilizes adult criteria (Bent and Kuhn's), with surgery and postoperative corticosteroids as primary treatment.
- Adjunctive therapies show potential but require further evidence.
Conclusions:
- Early diagnosis and comprehensive treatment are crucial for improving pediatric AFRS outcomes.
- Endoscopic sinus surgery to clear fungal burden and facilitate topical corticosteroids is the standard of care.
Related Concept Videos
Drugs Used in Upper Respiratory Disorders: Overview
Antihistamines (e.g., Benadryl) block histamines from binding. Histamines are chemicals released during an allergic reaction in the body. As a...
Drugs Used in Lower Respiratory Disorders: Overview
Bronchodilators, the first step of respiration enhancement, come in various forms, each with its own mechanism...
Cystic Fibrosis: Management
Sinus disease and chronic...
Pharmacokinetics in Pediatric Patients: Drug Excretion
Acute Respiratory Failure-V
Ensure that patients are monitored continuously for their response to therapy, including changes in...
Asthma: Pathogenesis and Management
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.

