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An Infant with COVID-19-Associated Intussusception
Gwyneth A Sullivan1, Nicholas J Skertich, Kody B Jones
1Department of Surgery, Division of Pediatric Surgery, Rush University Medical Center, Chicago, IL, USA.
Insights
This study suggests a link between COVID-19 and intussusception in infants, a common cause of bowel obstruction. Infants with intussusception should be screened for COVID-19, as symptoms can recur in different locations.
Area of Science:
- Pediatrics
- Infectious Diseases
- Gastroenterology
Background:
- Intussusception is a leading cause of bowel obstruction in infants aged 4-10 months.
- It is often idiopathic or linked to lymphoid hyperplasia.
Purpose of the Study:
- To investigate a potential association between COVID-19 and intussusception in infants.
- To highlight the possibility of recurrent intussusception at different locations.
Main Methods:
- Case report of a 7-month-old male infant presenting with recurrent intussusception.
- Diagnostic imaging included ultrasound and computed tomography (CT) scan.
- COVID-19 screening was performed.
Main Results:
- Initial ileocolic intussusception resolved with contrast enema.
- Recurrent ileal-ileal intussusception occurred days later in a different location.
- The patient tested positive for COVID-19 during the recurrent episode.
Conclusions:
- COVID-19 may be an etiological factor in infant intussusception.
- Screening infants with intussusception for COVID-19 is recommended.
- Caregiver education is crucial for monitoring potential recurrence.
Abstract:
Intussusception is the most common cause of bowel obstruction in infants four to ten months old and is commonly idiopathic or attributed to lymphoid hyperplasia. Our patient was a 7-month-old male who presented with two weeks of intermittent abdominal pain associated with crying, fist clenching and grimacing. Ultrasound demonstrated an ileocolic intussusception in the right abdomen. Symptoms resolved after contrast enemas, and he was discharged home. He re-presented similarly the next day and was found to be COVID-19 positive. Computed tomography scan demonstrated a left upper quadrant ileal-ileal intussusception. His symptoms spontaneously resolved, and he was discharged home. This suggests that COVID-19 may be a cause of intussusception in infants, and infants presenting with intussusception should be screened for this virus. Additionally, recurrence may happen days later at different intestinal locations. Caregiver education upon discharge is key to monitor for recurrence and need to return.
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