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Alcohol Consumption and Systemic Hypertension (from the Third National Health and Nutrition Examination Survey)
Amer I Aladin1, Parag A Chevli2, Muhammad Imtiaz Ahmad3
1Section of Interventional Cardiology, MedStar Georgetown University/Washington Hospital Center, Washington, District of Columbia.
Insights
Moderate to heavy alcohol consumption is linked to a higher prevalence of systemic hypertension (SH). This study analyzed 17,059 participants, finding increased odds of SH in moderate and heavy drinkers compared to non-drinkers.
Area of Science:
- Cardiology
- Epidemiology
- Public Health
Background:
- Excessive alcohol consumption is linked to systemic hypertension (SH).
- Associations between low to moderate alcohol intake and SH remain unclear.
- The 2017 ACC/AHA hypertension guidelines provide new blood pressure categorizations.
Purpose of the Study:
- To investigate the relationship between alcohol consumption patterns and blood pressure categories.
- To utilize the updated 2017 ACC/AHA hypertension guidelines for analysis.
- To examine associations in a large, representative US population sample.
Main Methods:
- Analysis of 17,059 participants from the Third National Health and Nutrition Examination Survey (NHANES).
- Alcohol consumption assessed via self-reported questionnaires.
- Blood pressure measured using standardized protocols; categorized using 2017 ACC/AHA guidelines.
- Multivariable logistic regression models adjusted for demographic and cardiovascular risk factors.
Main Results:
- Moderate drinkers (7-13 drinks/week) showed increased odds of prevalent stage 1 and stage 2 SH (ORs 1.51-1.55).
- Heavy drinkers (≥14 drinks/week) exhibited significantly higher odds of prevalent stage 1 and stage 2 SH (ORs 1.65-2.46).
- No significant association found between alcohol consumption and the 'elevated' blood pressure category.
Conclusions:
- Moderate and heavy alcohol consumption are associated with a higher prevalence of systemic hypertension.
- Self-reported alcohol intake may be subject to response bias.
- Further research is needed to elucidate the mechanisms linking alcohol consumption to SH risk.
Abstract:
Epidemiological studies have established the association between excessive alcohol consumption and systemic hypertension (SH). However, there are conflicting reports of the association of low to moderate alcohol consumption with SH. The objective of the study was to examine the associations of alcohol consumption and blood pressure categories using the 2017 American College of Cardiology/American Heart Association high blood pressure guidelines. This analysis included 17,059 participants from the Third National Health and Nutrition Examination Survey. Alcohol consumption was ascertained by way of a questionnaire. Blood pressure (mm Hg) was measured during the in-home interview and the participant's visit to the mobile examination center. We used multivariable logistic regression models to examine cross-sectional associations of alcohol consumption and blood pressure categories based on new American College of Cardiology/American Heart Association High Blood Pressure guidelines. Models were adjusted for age, gender, income, and cardiovascular risk factors. Compared with never drinkers, moderate drinkers (7 to 13 drinks/week) had increased odds of prevalent stage 1 and stage 2 SH (odds ratio [95% confidence interval] 1.51 [1.22 to 1.87] and 1.55 [1.20 to 2.00]). Similarly, there were significantly higher odds of prevalent stage 1 and stage 2 SH among heavy drinkers (≥14 drinks/week) (odds ratio [95% confidence interval] 1.65 [1.33 to 2.05] and 2.46 [1.93 to 3.14]). We did not find any association between alcohol consumption and elevated blood pressure category. Response bias must be considered because alcohol consumption was self-reported. Our study indicates the need for further research to understand the potential mechanisms by which alcohol consumption increases the risk of SH. In conclusion, this analysis from a population-based survey showed an association between moderate and heavy alcohol consumption and a higher prevalence of SH.
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