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Updated: Oct 19, 2025

Frailty Assessment in an Aging Mouse Model
Published on: September 23, 2025
Becoming frail: A more than human exploration
Victoria Cluley1, Nick Fox2, Zoe Radnor3
1University of Leicester, UK.
Frailty is more than a physical condition; it involves social, economic, and environmental factors. Understanding frailty as a dynamic
Area of Science:
- Gerontology
- Sociology of Health and Illness
- Qualitative Research Methods
Background:
- Frailty is clinically defined using quantitative measures of physical capacity.
- Qualitative research indicates social, economic, and environmental factors also contribute to frailty.
- Existing understandings often overlook the complex interplay of factors influencing frailty.
Purpose of the Study:
- To synthesize qualitative studies on frailty and aging from a new materialist perspective.
- To propose a relational understanding of frailty as a 'frailty assemblage'.
- To explore how materialities influence the 'becoming' of a frail body.
Main Methods:
- Systematic synthesis of recent qualitative research on frailty and aging.
- Application of new materialist theoretical frameworks.
- Analysis of daily activities and interactions of older people.
Main Results:
- Frailty is conceptualized not as a static attribute but as a dynamic 'frailty assemblage'.
- Material factors and daily interactions are integral to the ongoing 'becoming' of frailty.
- Clinical frailty is one manifestation within a complex web of influences.
Conclusions:
- A relational, more-than-human perspective is essential for understanding frailty.
- Acknowledging the complexity of 'becomings' is crucial for supporting frail older people.
- Interventions should consider the multifaceted nature of frailty beyond physical capacity.
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