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Updated: Oct 19, 2025

Palladium N-Heterocyclic Carbene Complexes: Synthesis from Benzimidazolium Salts and Catalytic Activity in Carbon-carbon Bond-forming Reactions
Published on: July 30, 2017
B-N bond formation through palladium-catalyzed, microwave-assisted cross-coupling of nitrogen compounds with
Mahmoud K Al-Joumhawy1, Tarek Marei1, Akim Shmalko1,2
1Department of Life Sciences and Chemistry, Jacobs University Bremen, Campus Ring 1, 28759 Bremen, Germany. D.Gabel@jacobs-university.de.
Abstract:
Substituted undecahydrido-closo-dodecaborates [B12H11NR2]2- have potential use in materials and drugs, but have presented a synthetic challenge. Microwave-assisted palladium-catalyzed amination of iodo-dodecaborate [B12H11I]2- allows mild and reproducible formation of B-N bonds with aromatic amines, HN-containing heteroaromatics, and amides. The reaction allows general access to amides, reproducible reactions to dodecaborate-substituted anilines, and, for the first time, the substitution of dodecaborate with HN-containing heterocycles.
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