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Kawasaki disease in adolescence and adulthood: Report of four cases

Hiroyuki Sakai1, Masako Minami-Hori1, Tomoe Shimamura1

  • 1Division of Dermatology, Asahikawa City Hospital, Asahikawa, Japan.

The Journal of Dermatology
|September 22, 2021
PubMed

Insights

Kawasaki disease (KD) is often missed in adults and adolescents because it primarily affects young children. Early recognition in older patients presenting with fever and rash is crucial for timely diagnosis and treatment.

Area of Science:

  • Pediatrics
  • Dermatology
  • Internal Medicine

Background:

  • Kawasaki disease (KD) typically affects children under 5 years old, leading to underdiagnosis in adolescents and adults.
  • Delayed diagnosis of KD can result in severe cardiovascular complications.

Observation:

  • This study presents four cases of KD in patients aged 16-32 years.
  • Initial consultations were with Otolaryngology, Obstetrics, or General Internal Medicine, highlighting diagnostic challenges.
  • Patients presented with fever and exanthem, common but non-specific symptoms.

Findings:

  • Kawasaki disease (KD) in older individuals often presents atypically, leading to delayed or missed diagnoses.
  • Cutaneous and mucosal manifestations are key indicators, emphasizing the role of dermatologists.
  • Prompt recognition of KD in febrile patients with rash, regardless of age, is essential.

Implications:

  • Increased awareness of adult and adolescent KD is necessary among healthcare providers.
  • Dermatologists play a critical role in identifying KD in non-infant populations.
  • Timely diagnosis and treatment of Kawasaki disease in all age groups can prevent long-term cardiac sequelae.

Keywords:
Kawasaki diseaseadolescenceadulthoodconjunctival injectionexanthem

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