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Updated: Oct 19, 2025

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Published on: February 26, 2013
Decision aids for shared decision-making and appropriate anticoagulation therapy in patients with atrial
Dan Song1, Jie Zhou1, Tianli Fan1
1Shenzhen Qianhai and Shekou Free Trade Zone Hospital, No. 36, 7th Industrial Road, Nanshan District, Shenzhen City, Guangdong Province 518067, P.R. China.
Insights
Decision aids (DAs) improve shared decision-making (SDM) and oral anticoagulant (OAC) uptake in atrial fibrillation (AF) patients. Evidence on OAC adherence and stroke/bleeding risk reduction remains uncertain, requiring further research.
Area of Science:
- Cardiology
- Evidence-Based Medicine
- Health Services Research
Background:
- Underuse of oral anticoagulants (OACs) is a significant issue in atrial fibrillation (AF) management, impacting stroke prevention.
- Shared decision-making (SDM) is crucial for enhancing treatment adherence and aligning care with patient preferences.
- Decision aids (DAs) are tools designed to facilitate SDM in clinical practice.
Purpose of the Study:
- To evaluate the impact of DAs on AF patients' knowledge, decisional conflict, OAC uptake, and adherence.
- To assess the effect of DAs on the incidence of stroke and bleeding in AF patients.
- To identify factors associated with improved effectiveness of DAs in promoting SDM and OAC use.
Main Methods:
- A systematic literature search was conducted across five databases.
- Meta-analysis was performed using RevMan 5.3 where data permitted.
- Comparative analysis identified characteristics of effective DAs, focusing on SDM elements and delivery methods.
Main Results:
- DAs significantly reduced decisional conflict regarding warfarin use (MD = -0.10, 95% CI: -0.18 to -0.02, P=0.01).
- DAs enhanced OAC uptake (RR = 1.03, 95% CI: 1.01-1.05, P=0.004).
- The effects of DAs on adherence, stroke, and bleeding incidence remain unclear. Effective DAs incorporated key SDM elements and were delivered pre-consultation.
Conclusions:
- Decision aids show promise in promoting SDM and OAC uptake among AF patients.
- Further rigorous trials with extended follow-up are needed to clarify the impact of DAs on adherence and clinical outcomes (stroke/bleeding).
- Specific DA design features, including comprehensive SDM components and pre-consultation delivery, are associated with greater effectiveness.
Aims:
Underuse of oral anticoagulants (OACs) is commonly observed among patients with atrial fibrillation (AF), which hinders stroke prevention in AF. Shared decision-making (SDM) can help enhance adherence by minimizing patients' misunderstanding of treatment and aligning care with their preferences. Decision aids (DAs) have been developed to facilitate the SDM process. This study aimed to: (i) evaluate the effects of DAs on AF patients' knowledge, decisional conflict, OAC uptake, and adherence and on the incidence of stroke and bleeding; and (ii) explore characterizing factors associated with enhanced DA effectiveness.
Methods And Results:
Five databases were searched. Meta-analysis was conducted using RevMan 5.3 when data were available. Comparative analysis between effective and ineffective DAs was conducted to determine the DA designs associated with better effects. Ten studies were included. Pooling results indicated that DAs reduce decisional conflict related to warfarin use [mean difference = -0.10; 95% confidence interval (CI): -0.18 to -0.02; P = 0.01] and enhance OAC uptake [risk ratio: 1.03; 95% CI: 1.01-1.05; P = 0.004]. The effects of DAs on adherence and incidence of stroke and bleeding were unclear. Comparative analysis revealed that DAs with key elements of SDM (situation diagnosis, choice awareness, option clarification, benefits and disadvantages, and patient's preference) and pre-consultation delivery are more likely to be effective in promoting SDM and OAC uptake.
Conclusions:
DAs are promising in promoting SDM and OAC uptake in patients with AF. The evidence on adherence and incidence of stroke and bleeding remains uncertain. More trials with rigorous study design and longer follow-up are necessary to obtain evidence.
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