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Combination of High Ligation and Intraoperative Embolization using Polidocanol for Treatment of Varicoceles
Published on: December 22, 2023
536
Varicocele treatment in non-obstructive azoospermia: a systematic review
Stephanie Jensen1, Edmund Y Ko1
1Department of Urology, Loma Linda University Health, Loma Linda, CA, USA.
Arab Journal of Urology
|September 23, 2021
Summary
Varicocele repair (VR) in men with non-obstructive azoospermia (NOA) can improve sperm retrieval rates and spontaneous pregnancy rates. VR may help some patients avoid assisted reproductive technologies, enhancing fertility outcomes.
Area of Science:
- Reproductive Medicine
- Urology
- Andrology
Background:
- Non-obstructive azoospermia (NOA) affects male fertility.
- Varicocele is a common cause of male infertility.
- The role of varicocele repair (VR) in NOA is debated.
Purpose of the Study:
- To identify factors associated with successful outcomes after varicocele repair (VR).
- To evaluate the impact of VR on spermatogenesis and pregnancy rates in men with NOA.
Main Methods:
- Systematic literature review of PubMed and EMBASE databases.
- Inclusion of 16 studies with an average sample size of 43 patients.
- Analysis of primary outcomes: return of spermatogenesis, sperm retrieval rates (SRRs), and pregnancy rates.
Main Results:
- Average rate of spermatogenesis post-VR was 27.3%.
- Average SRR was 48.9% in VR group vs. 32.1% in untreated NOA cohort.
- Average spontaneous pregnancy rate was 5.24%; histopathology subtype was a significant factor.
Conclusions:
- Varicocele repair is a viable option for men with NOA.
- VR can improve sperm retrieval and pregnancy rates.
- VR may reduce the need for assisted reproductive technologies in select NOA patients.
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