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Updated: Oct 19, 2025

Mechanical Ventilation Boot Camp Curriculum
Published on: March 12, 2018
Effective Implementation of Ventilator Care Bundles in Improves Outcomes: A Multicenter Randomized Controlled
Farshid Rahimi-Bashar1, Keivan Gohari-Moghadam2, Amir Vahedian-Azimi3
1Department of Anesthesiology and Critical Care, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.
Objectives:
To evaluate the effect of 17-ventilator care bundles and different training strategies for critical care nurses on clinical outcomes.
Design:
A randomized controlled triple-blinded clinical trial.
Setting:
The multicenter study was conducted in four academic teaching hospitals in Tehran, Iran, from October 2011 to June 2015.
Patients:
A total of 1,600 adult patients (age ≥ 18 yr) who were admitted to mixed medical-surgical ICUs (> 72 hr) and received invasive ventilation (> 48 hr) were included in this study. In addition, 160 critical care nurses were recruited through letters and telephone and face-to-face invitations.
Interventions:
Seventeen-ventilator care bundles applied by four different groups of nurses.
Measurements And Main Results:
Clinical outcomes were compared between four groups of study which include three intervention groups (who received 17-ventilator care bundles by trained nurses) and one control group (who received routine care). According to the results, ICU length of stay, non-ICU length of stay, ventilator-associated pneumonia occurrence date, ventilator-associated pneumonia, and mortality rates were significantly higher in control group compared with other groups.
Conclusions:
Critical care nurses training program to accurately implement 17-ventilator care bundles improves outcomes.
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