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More Adverse Events with Home Infusions.

Karen Rosenberg

The American Journal of Nursing

|September 23, 2021

Summary

Patients receiving biologic infusions at home for immune-mediated diseases faced higher risks of emergency department or hospital admission compared to those treated in facilities. Further safety evaluations of home biologic infusions are necessary.

Area of Science:

Immunology
Pharmacology
Health Services Research

Background:

Biologic therapies are increasingly used for immune-mediated diseases.
Home infusion services offer convenience but raise safety concerns.
Understanding the comparative safety of different administration settings is crucial.

Purpose of the Study:

To compare the safety of home versus facility-based biologic infusions for patients with immune-mediated diseases.
To assess the risk of emergency department (ED) or hospital admissions associated with different infusion settings.

Main Methods:

Retrospective analysis of patient data comparing home infusions versus facility-based infusions.
Inclusion of patients diagnosed with immune-mediated diseases receiving biologic infusions.

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Evaluation of admission rates to the ED or hospital within 24-48 hours post-infusion.

Main Results:

Patients receiving biologic infusions at home demonstrated a higher likelihood of ED or hospital admission.
The increased risk was observed on the day of infusion or the following day.
No specific patient or disease factors were detailed in the abstract regarding this increased risk.

Conclusions:

Home administration of biologic infusions for immune-mediated diseases may be associated with increased short-term risks of acute care utilization.
The safety profile of home biologic infusions requires further comprehensive investigation.
Healthcare providers should carefully consider the risks and benefits when recommending home infusion services.