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Transcriptional suppression of CD8+ T cell exhaustion for improving T cell immunotherapy

Xue Yang1, Bingjing Wang1, Xuetao Cao1,2

  • 1Department of Immunology, Institute of Basic Medical Sciences, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, 100005, P. R. China.

Cancer Communications (London, England)
|September 23, 2021
PubMed
Abstract

No abstract available in PubMed .

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Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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