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E-cigarette device and liquid characteristics and E-cigarette dependence: A pilot study of pod-based and disposable
Elizabeth K Do1, Katie O'Connor2, Siobhan N Perks2
1Schroeder Institute at Truth Initiative, Washington, DC, USA; Department of Health Behavior and Policy, Virginia Commonwealth University, USA; Department of Epidemiology, Milken Institute of Public Health, The George Washington University, Washington, DC, USA.
Nicotine flux from e-cigarettes is linked to higher dependence scores in pod-based device users. This study highlights how nicotine delivery impacts e-cigarette dependence.
Area of Science:
- Tobacco Control
- Addiction Science
- Public Health
Background:
- E-cigarette device and liquid characteristics influence nicotine emission rates (nicotine flux).
- Nicotine flux is hypothesized to impact user nicotine dependence.
- The E-cigarette Dependence Scale (EDS) measures nicotine dependence.
Purpose of the Study:
- To investigate the association between nicotine flux and nicotine dependence.
- To examine this relationship in users of pod-based and disposable e-cigarette products.
Main Methods:
- Online survey data from 1036 US adults (18-65 years) who were current or former e-cigarette users.
- Analysis included 666 participants providing device type, power, and nicotine concentration to calculate nicotine flux.
- Multivariable linear regressions assessed the relationship between nicotine flux and EDS, stratified by device type and adjusted for age and recent use.
Main Results:
- Higher nicotine flux was significantly associated with higher EDS scores among pod-based e-cigarette users (beta=0.19, p=0.043).
- No significant association was found between nicotine flux and EDS scores for disposable e-cigarette users.
- Neither device power nor nicotine concentration independently correlated with EDS scores for either device type.
Conclusions:
- Nicotine flux is positively associated with nicotine dependence among current users of pod-based e-cigarettes.
- Findings support the hypothesis that nicotine delivery rate influences e-cigarette dependence.
- Further research may explore device-specific nicotine delivery mechanisms and their impact on addiction.
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