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Updated: Oct 19, 2025

A TNBS-Induced Rodent Model to Study the Pathogenic Role of Mechanical Stress in Crohn's Disease
Published on: March 1, 2022
Anal neoplasia and perianal Crohn's disease: myth or reality?
Rodrigo Quera1, Paulina Núñez2, Luis Contreras3
1Enfermedad Inflamatoria Intestinal, Centro de Enfermedades Digestivas. Clínica Universidad de los Andes, Chile.
Abstract:
The association between inflammatory bowel disease (IBD) and anal canal squamous cell carcinoma (SCC) has a low prevalence and is mainly supported by articles that include a series of cases. We describe the clinical, endoscopic and histological findings of a patient with Crohn's disease (CD) who developed SCC while undergoing biological therapy with active disease.
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