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Localization and Relative Quantification of Carbon Nanotubes in Cells with Multispectral Imaging Flow Cytometry

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Endogenous Fluorescence Carbon Dots Derived from Food Items.

Haitao Wang^1,2, Wentao Su^1,2, Mingqian Tan^1,2

¹School of Food Science and Technology, National Engineering Research Center of Seafood, Dalian Polytechnic University, Qinggongyuan 1, Ganjingzi District, Dalian, Liaoning 116034, China.

Innovation (Cambridge (Mass.))

|September 24, 2021

Summary

Naturally occurring fluorescent carbon dots (CDs) in food, first identified in 2012, differ from engineered nanoparticles. Further research is needed to understand their long-term health effects.

Keywords:

fluorescent carbon dots food-borne nanoparticles potential risk toxicity

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Area of Science:

Nanomaterials Science
Food Science
Toxicology

Background:

Fluorescent carbon dots (CDs) are carbon-based nanomaterials discovered in 2004.
Naturally occurring CDs in food were identified in 2012.
Nanoparticle properties differ from bulk materials, impacting bioavailability and health risks.

Purpose of the Study:

To review existing literature on fluorescent carbon dots (CDs) in food.
To examine the properties and formation of food-borne CDs.
To assess potential health risks posed by food-borne CDs to consumers.

Main Methods:

Literature review of studies on fluorescent carbon dots in food.
Analysis of properties, formation, and safety data of food-borne CDs.
Identification of knowledge gaps in food-borne nanoparticle research.

Main Results:

Fluorescent CDs (<10 nm) found in processed foods contain carbon, oxygen, hydrogen, and/or nitrogen.
CDs form in food upon heating.
Food-borne CDs exhibit distinct properties compared to engineered nanoparticles.

Conclusions:

The presence and formation of fluorescent CDs in food during processing are documented.
Food-borne CDs represent a novel nanostructure with different properties than additives.
Limited in vivo and in vitro data necessitate further investigation into the chronic effects of CDs, despite low observed toxicity.