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Mirror therapy for unilateral neglect after stroke: A systematic review
Yuqian Zhang1, Ying Xing1, Congqin Li1
1Department of Rehabilitation Medicine, Huashan Hospital, Fudan University, Shanghai, China.
European Journal of Neurology
|September 24, 2021
Summary
Mirror therapy significantly improves neglect and daily living activities in stroke patients. This therapy offers a promising intervention for enhancing recovery and functional independence after unilateral neglect.
Area of Science:
- Neurorehabilitation
- Clinical Neuroscience
- Physical Therapy
Background:
- Unilateral neglect following stroke is a common and disabling condition.
- The efficacy of mirror therapy for unilateral neglect remains uncertain.
Purpose of the Study:
- To systematically review the effect of mirror therapy on neglect and daily living activities in stroke patients.
- To compare mirror therapy with no treatment, sham mirror therapy, or routine therapies.
Main Methods:
- Systematic electronic search of multiple databases (PubMed, Embase, Web of Science, etc.).
- Inclusion of five randomized controlled trials (RCTs) in the data synthesis.
- Meta-analysis of treatment effects using standard mean difference (SMD).
Main Results:
- Mirror therapy demonstrated superior effectiveness in improving neglect compared to sham or no treatment (SMD = 1.62, p < 0.00001).
- Mirror therapy also significantly enhanced daily living activities compared to control groups (SMD = 2.09, p = 0.005).
Conclusions:
- Mirror therapy is an effective intervention for improving both neglect and daily living activities in stroke survivors.
- Further high-quality, large-scale trials are recommended to establish optimal mirror therapy protocols and long-term effects.

