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Marcela Pacheco Cifuentes1

  • 1Unidad de Procedimientos del Centro de Consultas y Procedimientos, Hospital Clínico, Universidad de Chile, Santiago, Chile.

Journal of Wound Care
|September 24, 2021
PubMed
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Use of collagen and negative pressure wound therapy on a diabetic foot ulcer: a case study.

Journal of wound care·2022
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This case study shows collagen combined with negative pressure wound therapy effectively healed a diabetic foot ulcer. The treatment preserved the patient's independence and quality of life, avoiding amputation.

Area of Science:

  • Wound healing
  • Diabetic foot care
  • Regenerative medicine

Background:

  • Diabetic foot ulcers (DFUs) are a major cause of lower limb amputations.
  • Effective wound management is crucial for preventing complications in diabetic patients.
  • Advanced therapies are needed to improve DFU healing rates.

Purpose of the Study:

  • To describe the successful application of collagen and negative pressure wound therapy (NPWT) for a DFU.
  • To evaluate the efficacy of this combined treatment in a clinical setting.

Main Methods:

  • A collagen layer was applied to the DFU.
  • Negative pressure wound therapy (NPWT) was initiated over the collagen dressing.
  • Treatment was administered in a hospital setting.
Keywords:
collagencolágenodiabetesdiabetic footnegative pressure wound therapypie diabéticoterapia de presión negativaulcerúlcera

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Main Results:

  • The DFU size decreased by 58% within the initial 10 weeks of treatment.
  • Complete wound closure was achieved within 24 weeks.
  • The patient avoided lower limb amputation.

Conclusions:

  • The combination of collagen and NPWT is a viable and effective treatment for diabetic foot ulcers.
  • This therapeutic approach can significantly improve patient outcomes, preserving limb function and quality of life.