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Hepatic hemangioendothelioma - A rare case report
Kaleem Ullah1, Abdul Wahab Dogar1, Shams Uddin1
1Pir Abdul Qadir shah Jeelani Institute of Medical Sciences, Gambat, Sindh, Pakistan.
International Journal of Surgery Case Reports
|September 24, 2021
Summary
Hepatic hemangioendothelioma (HHE), a rare liver tumor, can be treated with liver transplantation for non-resectable cases. This case highlights successful living donor liver transplantation for multifocal HHE.
Area of Science:
- Hepatology
- Oncology
- Vascular Biology
Background:
- Hepatic hemangioendothelioma (HHE) is an exceptionally rare, mildly to moderately malignant tumor originating from hepatic vascular endothelium.
- Etiology remains unclear, with presentations ranging from asymptomatic to hepatic insufficiency.
- Diagnosis relies on imaging (CT, MRI) and confirmed by histology and immunohistochemistry.
Purpose of the Study:
- To report a case of non-resectable hepatic hemangioendothelioma treated with living donor liver transplantation.
- To discuss the management of rare hepatic vascular tumors.
Main Methods:
- A 19-year-old female with 9 months of right hypochondrium pain and hepatomegaly.
- Abdominal ultrasound and CT revealed hypoechoic lesions in both liver lobes.
- Diagnosis confirmed via ultrasound-guided fine-needle aspiration cytology.
- Successful living donor liver transplantation performed due to multifocal, bi-lobar disease.
Main Results:
- The patient underwent successful living donor liver transplantation for non-resectable HHE.
- At 8-month follow-up, the patient is in good health.
Conclusions:
- Surgical resection is preferred for resectable HHE.
- Liver transplantation is the treatment of choice for non-resectable, multifocal, and bi-lobar HHE.
- Long-term outcomes and recurrence rates for HHE require further investigation through extended follow-up studies.

