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Mitral valve prolapse in craniofacial skeletal deformities.
Oral Surgery, Oral Medicine, and Oral Pathology
|January 1, 1986
Summary
Mitral valve prolapse may be linked to connective tissue disorders and craniofacial deformities. Research suggests a potential causal relationship and a distinct facial profile in affected patients.
Area of Science:
- Cardiology
- Genetics
- Craniofacial Surgery
Background:
- Mitral valve prolapse (MVP) is associated with connective tissue disorders and mesenchymal dysplasia.
- Craniofacial deformities also stem from mesenchymal dysplasias, suggesting a potential link to MVP.
Purpose of the Study:
- To explore the relationship between mitral valve prolapse and orthognathic craniofacial deformities.
- To investigate the hypothesis that MVP patients exhibit a measurable, typical facial structure.
Main Methods:
- Review of embryologic development of the facial skeleton in relation to MVP.
- Observational analysis of MVP incidence in an orthognathic patient population.
- Proposal for cephalometric analysis to identify typical facial features in MVP patients.
Main Results:
- A slightly increased incidence of MVP was noted in the orthognathic patient group, though not statistically analyzed.
- The study suggests a potential, unquantified association between MVP and craniofacial deformities.
Conclusions:
- Mitral valve prolapse may be a manifestation of mesenchymal dysplasia, potentially linked to craniofacial deformities.
- Further cephalometric studies are warranted to confirm a characteristic facial phenotype in MVP patients.