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Update on Modulators of Quorum Sensing Pathways in Pseudomonas aeruginosa
Mohammad Anwar Hossain1, Nadezhda A German2
1Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC, United States.
Abstract:
Modulators of quorum sensing pathways in Pseudomonas aeruginosa (PA) gain attention due to their potential therapeutic applications. These chemical agents are viewed as anti-virulence agents capable of increasing the existing therapeutic agents' efficacy against resistant clinical strains. Additionally, they can be utilized in developing anticancer therapeutics, whole-cell biosensors, and artificial biological systems. In this mini-review, we summarize recent (2015-2021) publications on PA's QS modulation.
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