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Updated: Oct 19, 2025

Neuromodulation and Mitochondrial Transport: Live Imaging in Hippocampal Neurons over Long Durations
Published on: June 17, 2011
Two theories of action - Edelman's Neuronal group Selection and the Poetics of Paul Valéry
1Dactyl Foundation, 64 Grand Street, New York, NY, 10013, USA; STIAS, Stellenbosch Institute for Advanced Study, 10 Jean Marais Rd, Stellenbosch, SA, USA.
Abstract:
Motivated by two imperatives as they are framed in Code Biology - mechanism and actualization - we have turned to other attempts of modeling life at work. Here, we present two theories devoted to minds in action - one explains neuronal function, and the other dissects poetic crafting. Neuronal networks activation and poetic composition, respectively, are seen as the selection of specific connective patterns of either neurons or words, in action. Gerald Edelman, as a scientist, has generalized the Darwinian ideas of variation and selection to the cellular level in his "Sciences of Recognition", a broader theoretical framework that includes the "Theory of Neuronal Group Selection" (TGNS) analyzed here. Paul Valéry, as a poet, has reconciled inspiration and technique in what he has called "works of the mind", the creative processes mediated by sensing and making sense, in the "Poetic Theory" we present here he advances the mechanisms of artistic composition. We have identified the main ideas conveyed in these two theories, i.e., variation and selection, integration and differentiation, ambiguity and degeneracy, binding and blending, stasis and semiosis, by pairing and comparing textual fragments from the authors. We show that TGNS and the Theory of Poetic Action reconcile Sciences and Arts by recognizing that Natural Selection is a mechanism implied by formative acts in both scenarios and discuss to which extent Natural Convention - the main contribution of Code Biology - is integrated by the two thinkers.