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Making the cut with PAMless CRISPR-Cas enzymes.

Kathleen A Christie1, Benjamin P Kleinstiver1

  • 1Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, 02114, USA; Department of Pathology, Massachusetts General Hospital, Boston, MA, 02114, USA; Department of Pathology, Harvard Medical School, Boston, MA, 02115, USA.

Trends in Genetics : TIG
|September 26, 2021
PubMed
Summary

New CRISPR-Cas variants expand genome editing capabilities beyond natural enzyme limitations. These advancements allow scientists to precisely modify almost the entire genome, opening new avenues in genetic research.

Keywords:
CRISPRPAMgenome editingtargeting range

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