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Related Concept Videos

Heart Failure I: Introduction01:27

Heart Failure I: Introduction

157
Heart failure refers to a clinical syndrome caused by structural or functional cardiac disorders that prevent the heart from pumping an adequate amount of blood to meet the body's metabolic needs. This condition often arises from myocardial infarction or ischemia, leading to decreased cardiac output, reduced tissue perfusion, impaired gas exchange, fluid volume imbalance, and decreased functional ability.Heart failure can result from disruptions in the mechanisms that regulate cardiac output...
157
Pathophysiology of Heart Failure01:17

Pathophysiology of Heart Failure

2.0K
Heart failure (HF) is a progressive syndrome involving ventricles that leads to inadequate cardiac output. It can be classified based on location and output or ejection fraction. Ejection fraction (EF) is an essential measurement in the diagnosis and surveillance of HF. Reduced EF corresponds to systolic heart failure (HFrEF). However, HF with preserved ejection fraction (HFpEF) is becoming increasingly prevalent. Also known as diastolic HF, this form of HF is related to aging. The...
2.0K
Heart Failure III: Clinical Manifestations01:26

Heart Failure III: Clinical Manifestations

92
Heart failure (HF) manifests primarily as dyspnea, fatigue, and fluid retention, resulting in peripheral and pulmonary edema. Symptoms may vary depending on which ventricle is more affected, left or right.Left-Sided Heart FailureAlso known as left ventricular failure, this condition results from the left ventricle's inability to fill or eject sufficient blood into the systemic circulation. It leads to pulmonary congestion, which occurs when the left ventricle fails to eject blood effectively...
92
Heart Failure IV: Classification and Diagnostic Evaluation01:30

Heart Failure IV: Classification and Diagnostic Evaluation

74
Heart failure can be classified in various ways, with the most common classifications based on physical activity limitations, disease progression, severity, and treatment strategies.The Functional Classification of Heart Failure divides patients into four categories based on physical activity limitation due to symptom burden.Class I: Patients in this class have cardiac disease but no physical activity limitations. Ordinary activities like walking, climbing stairs, or routine tasks do not cause...
74
Heart Failure II: Pathophysiology01:29

Heart Failure II: Pathophysiology

105
Systolic Heart Failure and Compensatory MechanismsSystolic heart failure (also termed HFrEF, Heart Failure with Reduced Ejection Fraction) is the most prevalent type of heart filure. It results in a decreased volume of blood being pumped from the ventricle. The aortic arch and carotid sinuses have baroreceptors that detect reduced blood pressure, triggering the sympathetic nervous system (SNS) to release epinephrine and norepinephrine. Initially, this response aims to boost heart rate and...
105
Heart Failure VII: Nursing Interventions01:30

Heart Failure VII: Nursing Interventions

193
The first step in nursing management of a patient with heart failure involves thoroughly assessing the patient's medical history.Subjective Data: Obtain the patient's medical history of coronary artery disease, hypertension, myocardial infarction, and symptoms like dyspnea, orthopnea, and paroxysmal nocturnal dyspnea.Objective Data: Conduct a physical examination to identify findings such as jugular vein distention, pulmonary crackles, tachycardia, murmurs, peripheral edema, and vital signs,...
193

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Related Experiment Video

Updated: Oct 19, 2025

A Surgical Model of Heart Failure with Preserved Ejection Fraction in Tibetan Minipigs
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A Surgical Model of Heart Failure with Preserved Ejection Fraction in Tibetan Minipigs

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Heart failure disease: An African perspective.

Imen Gtif1, Fériel Bouzid1, Salma Charfeddine2

  • 1Laboratory of Molecular and Cellular Screening Processes, Centre of Biotechnology of Sfax, University of Sfax, Sidi Mansour, 3061 Sfax, Tunisia.

Archives of Cardiovascular Diseases
|September 26, 2021
PubMed
Summary

Heart failure is a major health issue in Africa, with varied causes and challenges in diagnosis and treatment. More research and registries are needed to improve patient outcomes across the continent.

Keywords:
AetiologyAfrique subsaharienneHeart failureInsuffisance cardiaqueManagementNord d’AfriqueNorth AfricaPrise en chargeSUB-Saharan AfricaÉtiologie

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Area of Science:

  • Cardiology
  • Public Health
  • Epidemiology

Background:

  • Heart failure presents a significant health challenge in Africa, marked by high hospitalization, morbidity, and mortality rates.
  • Existing data on heart failure epidemiology, etiology, and management in Africa is limited, particularly regarding patient demographics.

Purpose of the Study:

  • To review and synthesize recent data on heart failure in Africa, comparing North Africa and sub-Saharan Africa.
  • To identify common etiologies, risk factors, and management strategies for heart failure across different African regions.
  • To highlight challenges in diagnosis and treatment, and advocate for improved healthcare infrastructure and research.

Main Methods:

  • A comprehensive literature review of recent studies on heart failure in North Africa and sub-Saharan Africa.
  • Analysis of data on prevalence, etiology, risk factors, and management strategies.
  • Comparison of heart failure characteristics between North African and sub-Saharan African countries.

Main Results:

  • Common causes of heart failure in Africa include ischemic heart disease, hypertensive heart disease, dilated cardiomyopathy, and valvular heart disease.
  • Etiology and clinical presentation of heart failure differ between North Africa and sub-Saharan Africa, influenced by socioeconomic factors and diagnostic tool availability.
  • Diagnosis and treatment are hampered by a lack of essential diagnostic tools and necessary human resources, especially in sub-Saharan Africa where key medications are often unavailable.

Conclusions:

  • There is a critical need for a large, multicenter registry to accurately assess the burden of heart failure in Africa.
  • Improvements in early diagnosis, treatment accessibility, and preventative strategies are essential.
  • Addressing the disparities in resources and healthcare infrastructure is crucial for managing heart failure effectively across the continent.