Sutureless Versus Rapid Deployment Aortic Valve Replacement: Results From a Multicenter Registry.

Area of Science:

• Cardiovascular Surgery
• Medical Devices
• Clinical Outcomes

Background:

• Sutureless and Rapid Deployment Aortic Valve Replacement (SURD-AVR) represents an evolving approach to treating aortic valve disease.
• Large-scale registries are crucial for comparing clinical and hemodynamic outcomes of different SURD-AVR technologies.

Purpose of the Study:

• To compare the in-hospital clinical and hemodynamic outcomes of sutureless (Perceval) versus rapid deployment (Intuity) aortic valve replacement.
• To evaluate the safety and efficacy of these two SURD-AVR valve types in a large patient cohort.

Main Methods:

• Analysis of 4695 patients from the Sutureless and Rapid Deployment International Registry (SURD-IR).
• Propensity score matching created balanced cohorts for isolated (823 pairs) and combined (467 pairs) SURD-AVR.
• Comparison of clinical endpoints including mortality, complications, operative times, and hemodynamic parameters.

Main Results:

• Both Perceval and Intuity valves demonstrated similar in-hospital mortality and major complication rates.
• Perceval valve use was associated with shorter cross-clamp and cardiopulmonary bypass times.
• Intuity valve showed significantly lower postoperative transvalvular gradients and a reduced rate of mild aortic regurgitation.

Conclusions:

• Sutureless and Rapid Deployment Aortic Valve Replacement (SURD-AVR) is safe and effective, irrespective of the specific valve used.
• The Perceval valve is linked to reduced operative times and a higher likelihood of anterior right thoracotomy.
• The Intuity valve offers superior hemodynamic performance and a lower incidence of mild postoperative aortic regurgitation.