Brugada Pattern in a Child with Severe SARS-CoV-2 Related Multisystem Inflammatory Syndrome
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Published on: July 5, 2021
Angelica De Nigris1, Angela Pepe2, Giangiacomo Di Nardo3
1Department of Woman, Child and General and Specialist Surgery, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.
Insights
This case report details a child with Multisystem Inflammatory Syndrome in Children (MIS-C) who developed a Brugada pattern and supraventricular arrhythmias. It highlights the complex cardiac management required in such pediatric cases.
Area of Science:
- Pediatric Cardiology
- Infectious Diseases
- Electrophysiology
Background:
- Multisystem Inflammatory Syndrome in Children (MIS-C) is a serious condition following SARS-CoV-2 infection.
- Brugada pattern is an inherited cardiac condition that can increase the risk of sudden cardiac death.
- Supraventricular arrhythmias are abnormal heart rhythms originating above the ventricles.
Observation:
- A 7-year-old boy presented with symptoms consistent with MIS-C.
- Electrocardiogram (ECG) revealed a type 1 Brugada pattern upon admission.
- The child subsequently experienced supraventricular arrhythmias during hospitalization.
Findings:
- This is the first reported case of Brugada pattern complicated by supraventricular arrhythmia in a child with MIS-C.
- The co-occurrence presents unique diagnostic and management challenges.
- ECG findings indicated significant cardiac electrical abnormalities.
Implications:
- This case underscores the importance of cardiac monitoring in children with MIS-C.
- It highlights the complexity of managing supraventricular arrhythmias in patients with Brugada pattern and systemic inflammation.
- Careful consideration of all therapeutic options is crucial for optimal patient outcomes.
Abstract:
This report presents the first case of Brugada pattern complicated by a supraventricular arrhythmia in a child with SARS-CoV-2 related Multisystem Inflammatory Syndrome in Children (MIS-C). A 7-year-old boy came to our Emergency Department with 7 days of abdominal pain and fever. MIS-C was diagnosed on the basis of the clinical, laboratory and instrumental tests. On admission, ECG showed type 1 Brugada pattern in the right precordial leads. During hospitalization the onset of supraventricular arrhythmias complicated the clinical picture. This case underlines management complexity of supraventricular arrhythmic events, different from atrial fibrillation, in patients with Brugada pattern in the context of a systemic inflammatory condition with significant cardiac involvement. All potential therapeutic choices should be considered to ensure the best outcomes.
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