Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy01:30

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy

456
Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
456
Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

461
Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
461
Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT01:25

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT

161
Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...
161

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Temporal AI-assisted compressed sensing for high-resolution, motion-robust small-bowel MR enterography without antiperistaltic agents: a feasibility study.

European radiology·2026
Same author

Noninvasive Prediction of High Ki-67 Expression in Hepatocellular Carcinoma Using Multiparametric MRI and Clinical Biomarkers.

Journal of hepatocellular carcinoma·2026
Same author

Comprehensive evaluation for transplant renal arterial morphology, hemodynamics, and renal function: utilizing non-contrast 4D flow MRI.

International journal of surgery (London, England)·2026
Same author

MRI evaluation of obturator internus muscle: its relationship with body composition and prognostic implications in prostate cancer patients undergoing ADT.

European radiology·2025
Same author

Comparison of reduced field-of-view DWI with conventional DWI for machine learning-based assessment of lymphovascular invasion in rectal cancer.

Medical physics·2025
Same author

Enhancing postoperative recurrence assessment in gastric and colorectal cancer patients with intraperitoneal fluorouracil implants: overcoming the diagnostic challenge of fluorouracil implant-related tumor-like lesions.

Quantitative imaging in medicine and surgery·2025

Related Experiment Video

Updated: Oct 19, 2025

Segmentation and Linear Measurement for Body Composition Analysis using Slice-O-Matic and Horos
13:35

Segmentation and Linear Measurement for Body Composition Analysis using Slice-O-Matic and Horos

Published on: March 21, 2021

10.9K

Computed tomography-based multiple body composition parameters predict outcomes in Crohn's disease.

Ziling Zhou1,2, Ziman Xiong1, Qingguo Xie2

  • 1Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Avenue, Wuhan, 430030, Hubei, China.

Insights Into Imaging
|September 26, 2021
PubMed
Summary
This summary is machine-generated.

Body composition analysis using computed tomography can predict Crohn's disease behavior and outcomes. Low skeletal muscle is linked to complicated disease, while fat distribution predicts adverse events.

Keywords:
Body composition parameterComputed tomographyCrohn’s disease

More Related Videos

Author Spotlight: Advancements in 3D Optical Imaging for Comprehensive Body Composition Assessment in Modern Research
06:48

Author Spotlight: Advancements in 3D Optical Imaging for Comprehensive Body Composition Assessment in Modern Research

Published on: June 7, 2024

1.6K
Segmentation and Measurement of Fat Volumes in Murine Obesity Models Using X-ray Computed Tomography
13:09

Segmentation and Measurement of Fat Volumes in Murine Obesity Models Using X-ray Computed Tomography

Published on: April 4, 2012

16.3K

Related Experiment Videos

Last Updated: Oct 19, 2025

Segmentation and Linear Measurement for Body Composition Analysis using Slice-O-Matic and Horos
13:35

Segmentation and Linear Measurement for Body Composition Analysis using Slice-O-Matic and Horos

Published on: March 21, 2021

10.9K
Author Spotlight: Advancements in 3D Optical Imaging for Comprehensive Body Composition Assessment in Modern Research
06:48

Author Spotlight: Advancements in 3D Optical Imaging for Comprehensive Body Composition Assessment in Modern Research

Published on: June 7, 2024

1.6K
Segmentation and Measurement of Fat Volumes in Murine Obesity Models Using X-ray Computed Tomography
13:09

Segmentation and Measurement of Fat Volumes in Murine Obesity Models Using X-ray Computed Tomography

Published on: April 4, 2012

16.3K

Area of Science:

  • Radiology and Imaging
  • Gastroenterology
  • Nutritional Science

Background:

  • Computed tomography (CT)-based body composition analysis in Crohn's disease (CD) lacks comprehensive evaluation for disease behavior and prognosis.
  • This study investigates CT-derived body composition parameters' association with CD behavior and outcomes.

Purpose of the Study:

  • To assess the link between body composition parameters and Crohn's disease behavior and outcomes.
  • To compare the efficacy of body composition indexes derived from body height versus lumbar spinal height.
  • To identify predictors of disease course and adverse outcomes in Crohn's disease patients.

Main Methods:

  • Retrospective analysis of 122 Crohn's disease patients with abdominal CT scans.
  • Calculation of skeletal muscle, visceral, and subcutaneous fat indexes using height squared and lumbar spinal height squared.
  • Multivariate analysis and principal component analysis to identify predictors of disease behavior and adverse outcomes.

Main Results:

  • Indexes derived from body and lumbar spinal heights showed strong correlation (r > 0.934, p < 0.001).
  • Low skeletal muscle index was significantly associated with complicated Crohn's disease behavior (p = 0.048).
  • Complicated disease behavior (p < 0.001) and adipose tissue distribution (p = 0.029) independently predicted adverse outcomes.

Conclusions:

  • Skeletal muscle and adipose tissue components are associated with complicated Crohn's disease behavior and adverse outcomes, respectively.
  • CT-based body composition analysis provides valuable insights into Crohn's disease prognosis.
  • Body height and lumbar spinal height derived indexes are equally effective for body composition assessment in Crohn's disease.