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Dyslipidemia in pediatrician's practice.
Alla V Burlutskaya1, Victoria E Tril1, Lily V Polischuk2
1Department of Pediatrics №2, Kuban State Medical University, 350063 Krasnodar, Russia.
Reviews in Cardiovascular Medicine
|September 26, 2021
Summary
Atherosclerosis, a leading cause of death, begins in childhood. Early detection of lipid metabolism disorders (dyslipidemias) in children is crucial for preventing future cardiovascular diseases.
Area of Science:
- Cardiology
- Pediatric Health
- Metabolic Disorders
Background:
- Atherosclerosis is a leading cause of cardiovascular mortality, with pathological processes beginning in early life.
- Risk factors for atherosclerosis, including dyslipidemias, are prevalent in children and adolescents.
- Childhood lipid profiles predict adult cardiovascular risk, necessitating early intervention.
Purpose of the Study:
- To investigate the pathophysiological basis of lipid and lipoprotein metabolism.
- To examine the epidemiology of dyslipidemias in children and adolescents.
- To review dyslipidemia classification, diagnosis, and management strategies for pediatric populations.
Main Methods:
- Epidemiological studies on pediatric dyslipidemia prevalence.
- Analysis of pathophysiological mechanisms of lipid metabolism.
- Review of current diagnostic and therapeutic guidelines for pediatric dyslipidemias.
Main Results:
- Dyslipidemias are highly prevalent in over 70% of children and adolescents globally.
- Childhood dyslipidemias are significant predictors of adult cardiovascular disease.
- Early identification of dyslipidemia enables preclinical risk stratification.
Conclusions:
- Dyslipidemia is a critical, early-onset risk factor for atherosclerotic cardiovascular diseases.
- Timely diagnosis and management of pediatric dyslipidemias are essential for long-term cardiovascular health.
- Phenotyping dyslipidemias in youth aids in identifying individuals at high risk for future cardiovascular pathology.
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