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[Skin and soft tissue infection caused by Streptococcus pneumoniae: report of 15 cases]

S Pérez de Madrid1, A M Rodrigo, D Tena

  • 1Sara Pérez de Madrid, Sección de Microbiología, Hospital General Universitario de Guadalajara. C/. Donante de sangre s/n. 19002 Guadalajara. Spain. sperezde@sescam.jccm.es.

Revista Espanola De Quimioterapia : Publicacion Oficial De La Sociedad Espanola De Quimioterapia
|September 27, 2021
PubMed
Abstract

Insights

Streptococcus pneumoniae rarely causes skin and soft tissue infections (SSTI), but should be considered in patients with cancer or immunosuppression. Most cases resolve favorably, though necrotizing fasciitis requires close attention.

Area of Science:

  • Infectious Diseases
  • Microbiology
  • Dermatology

Background:

  • Streptococcus pneumoniae is an uncommon cause of skin and soft tissue infections (SSTI).
  • Understanding the clinical and microbiological aspects of S. pneumoniae-related SSTIs is crucial for effective management.

Observation:

  • A retrospective review identified 15 cases of SSTIs caused by S. pneumoniae between 2012 and 2020.
  • The majority of patients (73.3%) had underlying conditions, primarily neoplasias, and predisposing factors like immunosuppression (60%).
  • Clinical presentations varied, including abscesses, ulcers, surgical site infections, lactational mastitis, and necrotizing fasciitis.

Findings:

  • Polymicrobial infections were present in 73.3% of cases, with a nosocomial etiology in 6.6%.
  • The clinical course was favorable in 90.9% of patients.
  • High sensitivity rates were observed for cefotaxime, levofloxacin, vancomycin, linezolid, and rifampicin against S. pneumoniae.

Implications:

  • S. pneumoniae should be considered in the differential diagnosis of SSTIs, particularly in immunocompromised patients and those with cancer.
  • The pathogen's role in severe infections like lactational mastitis and necrotizing fasciitis warrants attention.
  • While most cases have a good prognosis, severe presentations necessitate prompt and appropriate antimicrobial therapy.
Keywords:
Streptococcus pneumoniaemastitisnecrotizing fasciitispneumococcusskin and soft tissue infectionskin ulcersurgical wound infectionwound infection

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