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Updated: Oct 19, 2025

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Fertility Preservation Through Oocyte Vitrification: Clinical and Laboratory Perspectives
Published on: September 16, 2021
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Trainee-Led Quality Improvement Project to Improve Fertility Preservation Counseling for Patients With Cancer
Laura A Sena1, Ramy Sedhom1,2,3, Susan Scott1
1The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD.
JCO Oncology Practice
|September 27, 2021
Summary
Oncofertility counseling rates for cancer patients aged 18-40 increased from 37% to 81% after implementing a trainee-led initiative. This patient-centered approach improved reproductive health discussions during cancer therapy.
Area of Science:
- Oncology
- Reproductive Medicine
- Healthcare Quality Improvement
Background:
- Oncofertility counseling is crucial for patients undergoing cancer therapy.
- Reproductive risks associated with cancer treatments necessitate informed patient discussions.
- Baseline oncofertility counseling rates at Johns Hopkins Cancer Center were 37%.
Purpose of the Study:
- To increase oncofertility counseling rates for reproductive-aged cancer patients initiating systemic therapy.
- The target was to raise counseling rates from 37% to 70% by February 2021.
Main Methods:
- An interprofessional team utilized Plan-Do-Study-Act (PDSA) cycles for quality improvement.
- Data were collected via electronic medical records and patient phone verification.
- Barriers were identified through surveys of patients, oncologists, and fertility specialists.
Main Results:
- Key barriers included lack of oncologist knowledge and a non-standardized referral process.
- Interventions involved educational sessions, patient pamphlets, and an electronic medical record order set.
- Post-implementation, counseling rates significantly increased to 81%.
Conclusions:
- A trainee-led, patient-centered initiative effectively enhanced oncofertility care.
- Future efforts will focus on sustaining these improvements and evaluating counseling quality.
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