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Murine Appendectomy Model of Chronic Colitis Associated Colorectal Cancer by Precise Localization of Caecal Patch

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Multiple caecal granular cell tumours-a case report.

Kar Yin Fok¹, Chow Heok P'Ng², Hema Mahajan²

¹Department of Colorectal Surgery, Westmead Hospital, Westmead, New South Wales, Australia.

Journal of Surgical Case Reports

|September 27, 2021

Summary

This summary is machine-generated.

Multiple granular cell tumors (GCTs) in the cecum are rare but important to consider. This case highlights the need for awareness of these generally benign neoplasms, even when atypical features are present.

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Area of Science:

Gastroenterology
Surgical Pathology
Oncology

Background:

Granular cell tumors (GCTs) are neoplasms of generally benign nature, originating from neural cells.
GCTs are infrequently observed in the gastrointestinal tract, with colonic occurrences being even rarer.
Multiple GCTs in the colon are exceptionally uncommon.

Purpose of the Study:

To report a rare case of multiple cecal granular cell tumors with cellular atypia.
To emphasize the importance of considering GCTs in the differential diagnosis of colonic submucosal lesions.
To discuss the implications for patient management when encountering GCTs.

Main Methods:

A case presentation of a patient undergoing right hemicolectomy for colonic lesions.
Histopathological diagnosis of multiple nodules as cecal GCTs with cellular atypia.

Main Results:

The patient was diagnosed with multiple granular cell tumors in the cecum.
The tumors exhibited cellular atypia, a less common feature.

Conclusions:

Multiple GCTs of the cecum, though rare, warrant consideration in clinical practice.
Awareness of GCTs is crucial for appropriate patient management due to their typically benign behavior.
Cellular atypia in GCTs does not necessarily indicate malignancy and requires careful evaluation.