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Serratia marcescens Endocarditis
Sherif Elkattawy1, Mahsa Mohammadian1, Neil Williams2
1Internal Medicine, Rutgers-New Jersey Medical School/Trinitas Regional Medical Center, Elizabeth, USA.
Infective endocarditis (IE) caused by Serratia marcescens, a Gram-negative bacteria, is rare but serious. This report details two complex cases, highlighting the severity and management challenges of S. marcescens IE.
Area of Science:
- Infectious Diseases
- Cardiology
- Microbiology
Background:
- Infective endocarditis (IE) is most commonly caused by Staphylococcus aureus and Streptococcus species.
- Gram-negative bacterial IE, particularly by Serratia marcescens, is infrequent.
- Intravenous drug use (IVDU) is a presumed risk factor for Serratia marcescens IE.
Observation:
- Two cases of IE caused by Serratia marcescens are presented.
- The first case involved IE of the tricuspid and aortic valves, necessitating surgery and complicated by an epidural abscess.
- The second case presented with associated renal and splenic infarcts.
Findings:
- Serratia marcescens IE can lead to severe and complicated clinical presentations.
- These cases underscore the potential for significant morbidity associated with this rare form of IE.
- The reported cases contribute to the limited literature on Serratia marcescens IE incidence and clinical course.
Implications:
- Highlights the importance of considering Gram-negative pathogens in IE, especially in at-risk populations.
- Emphasizes the need for prompt diagnosis and aggressive management of Serratia marcescens IE.
- Provides valuable data for understanding the clinical spectrum and outcomes of Serratia marcescens IE.
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